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放射線照射가 口蓋形成期에 미치는 影響에 關한 實驗的硏究
EXPERIMENTAL STUDY ON THE EFFECT OF RADIATION IN THE SECONDARY PALATE FORMATION

치과방사선 1977년 7권 1호 p.9 ~ 15

류동수,

소속 상세정보

류동수 ( ) - 서울대학교 치과대학 방사선학교실

KMID : 0378219770070010009

Abstract

The author observed the effct of X-ray irradiation on the secondary palate fromation of the rat fetuses.
The mothers were exposed to X-radiation on the 10th, 11th and 12th day of gestation with respectively 150, 200, 250, 300 and 350 rads. The fetuses were removed form mothers on 15th, 16th and 18th day of gestation.
Morphological changes in palate formation were examined and histochemical preparations were made.
1. In control fetuses, the secondary palates were fully developed on the 15th to 18th day of gestatin. But in experimental fetuses, many cleft palates were observed in accordance with increase of X-radiation dose.
2. Frequency of incidence of horizontal position of both palated shelves in cleft palate was highest.
3. According to the dislocation of palatal processes, the stain ability of palatal crest was varied.
4. The thickened area of palatal epithelim of palatalcrest showed intense methyl green-pryronin and PAS reaction
5. Mesenchymal cell condensatin was appeared under the thickened epithelium of palatal process and this mesenchymal tissue showed strong colloidal iron reaction.
6. The stain ability of alizaring red S and alkaline phosphatase reaction of tectal ridge were decreased, in accordance with increase of irradiation doses.